The GeneRead DNA QuantiMIZE System is a qPCR-based approach to determine quantity and quality of DNA that is amenable to amplification by targeted enrichment prior to NGS. The system has been developed for discovery, translational, and clinical researchers who need a cost-effective way to determine the optimum conditions for targeted enrichment of DNA isolated from biological samples, including FFPE. In contrast to other approaches, the system improves the likelihood of a successful NGS run by not only quantifying amplifiable DNA, but also optimizing the target enrichment conditions.