Plant miRNAs play a necessary role in processes such as development, disease resistance and stress response. These small non-coding RNAs are thought to regulate gene expression in plants at the post-transcriptional level by targeting mRNAs for cleavage. These targeted alterations in gene expression are mediated by differential expression of hundreds of mature miRNAs that each bind to specific sequences in the target mRNAs. Therefore, profiling to coordinate regulation and expression of mature plant miRNAs provides invaluable insight into mechanisms that an organism is using to develop tissue, protect itself from drought or fend off disease. Until now, universal profiling of mature plant miRNAs by qRT-PCR was virtually nonexistent because polyadenylation-based reverse transcription reactions occur with very low efficiency due to the biochemical nature of plant miRNAs. QIAGEN has released a unique solution that allows universal reverse transcription of all mature plant miRNAs in a tissue. Learn how profiling miRNAs in plants can accelerate your research today!