The Aurum vacuum manifold serves as a vacuum purification platform for either 96-well plates or individual luer-ended spin columns, ensuring fast, high-quality sample preparation. The vacuum manifold streamlines sample purification, maintaining the handling simplicity associated with vacuum processing while sustaining optimal steady-state vacuum pressure. It is compatible with Bio-Rad’s Aurum total RNA kits, the Aurum plasmid mini kit, and the Bio-Plex 200 suspension array system.