Single-cell transcriptomics is important in understanding how gene expression of individual cells varies within cell populations. We have developed an end-capture method that focuses the majority of sequencing data on the 3′ ends of mRNA transcripts from single cells. This enables you to collect high quality data with fewer sequencing reads. This kit incorporates features from the industry-leading SMART-Seq v4 kit, including SMART (Switching Mechanism at 5′ End of RNA Template) and locked nucleic acid (LNA) technology.