The rabbit Anti-5-hmC Polyclonal Antibody can robustly distinguish between hydroxymethylated DNA and methylated or unmodified DNA with limited to no cross-reactivity. The antibody has been validated in ELISA and immunoprecipitation based enrichment assays, and is suitable for use in further applications including immunohistochemical labeling and chromatographic blotting.
Low cross reactivity with Cytosine and 5-methylcytosine versus other available antibodies. Can be used with a variety of genomic DNA sources.
High sensitivity to low masses of 5-Hydroxymethylcytosine DNA.