The Ion PI™ Chip Kit v3 contains 8 barcoded chips for sample tracking and sequencing with the Ion Proton™ System. The Ion PI™ Chip electronically detects polymerase-driven base incorporation without the use of fluorescence. By eliminating the use of an optical detection system, this revolutionary advance in next-generation sequencing technology allows for rapid sequencing times of less than 4 hours. The Ion PI™ Chip v3 enables a simplified sequencing workflow with the removal of chip preparation steps, reducing the hands-on time by approximately 45 minutes compared to previous versions.