The pSV40-CLuc Control Plasmid is a mammalian expression vector that encodes the secreted luciferase from the Ostracod Cypridina noctiluca (1) as a reporter, under the control of the constitutive SV40 promoter. Cypridina Luciferase (CLuc) is a 62 kDa protein with a native signal peptide at the N-terminus that allows it to be secreted from mammalian cells (1) so that CLuc activity can be detected in the culture medium. There is a multiple cloning site (MCS) upstream of the SV40 promoter.