The RNeasy 96 BioRobot 8000 Kit provides high-throughput purification of total RNA from up to 96 cultured-cell samples using silica-membrane RNeasy 96 plates. Automated purification is performed using the BioRobot Universal System, which processes up to 96 or 192 samples per run followed by real-time RT-PCR setup. Manual purification with the related RNeasy 96 Kit is carried out using the QIAGEN 96-Well–Plate Centrifugation System and/or the QIAvac 96 vacuum manifold.