10X ThermoPol Reaction Buffer is optimized for use with VentR® and Deep VentR™ DNA Polymerases. This buffer also provides superior reaction conditions for other thermophilic DNA polymerases, including Taq DNA Polymerase, as well as various other DNA and RNA modifying enzymes. Supplemental MgSO4 is provided to maximize flexibility for users that require additional Mg2+ for their specific application. See individual product descriptions for the recommended buffer for each enzyme, or visit the FAQ page for this product on the NEB web site for a complete list of enzymes for which this buffer is either recommended or compatible.