The pSV40-GLuc Control Plasmid is a mammalian expression vector that encodes the secreted luciferase from the copepod Gaussia princeps as a reporter, under the control of the constitutive SV40 promoter. Gaussia luciferase (GLuc) is a 19 kDa protein encoded by a “humanized “ sequence, and it contains a native signal peptide at the N-terminus that allows it to be secreted from mammalian cells into the cell culture medium (1) There is a multiple cloning site (MCS) upstream of the SV40 promoter.